NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance
#1PRI RANKED
Most Cited Paper
in DNA Repair Mechanisms
18 Months Post-Publication
Class of 2026
“NBS1 lactylation is required for efficient DNA repair and chemotherapy resistance”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/dna-repair-mechanisms/2026/
Topics
NBS1 lactylation · lysine 388 (K388) · Warburg effect · lactate accumulation · Homologous recombination · DNA double-strand breaks · MRN complex · TIP60 · lysine lactyltransferase · HDAC3 · de-lactylase · lactate dehydrogenase A (LDHA) · stiripentol · Chemoresistance · neoadjuvant chemotherapy · Genome integrity · anaerobic glycolysis · DNA repair efficacy
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Pepkio Research Index (PRI). Topics and Trends in Most Cited DNA Repair Mechanisms Papers, Class of 2026. https://pri.pepkio.com/top-papers/dna-repair-mechanisms/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459