In vivo editing of lung stem cells for durable gene correction in mice
Most Cited Paper
in CRISPR and Genetic Engineering
18 Months Post-Publication
Class of 2026
“In vivo editing of lung stem cells for durable gene correction in mice”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/crispr-and-genetic-engineering/2026/
Topics
Lipid nanoparticle · In vivo genome editing · lung stem cells · Adenine base editor · NG-ABE8e · Cystic Fibrosis · CFTR · R553X nonsense mutation · F508del · Intravenous administration · tdTomato reporter mice · patient-derived bronchial epithelial cells · intestinal organoids · Trikafta · Gene correction · CFTR function restoration · sgR553X · lung epithelial cells · CF mouse model
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Pepkio Research Index (PRI). Topics and Trends in Most Cited CRISPR and Genetic Engineering Papers, Class of 2026. https://pri.pepkio.com/top-papers/crispr-and-genetic-engineering/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459