FOXO1 enhances CAR T cell stemness, metabolic fitness and efficacy

Topics

FOXO1 · CAR T cells · stemness · metabolic fitness · solid tumours · CAR T cells · stem-like phenotype · mitochondrial mass · mitochondrial fitness · immunosuppressive tumour microenvironment · T cell persistence · Transcription factors · acute lymphoblastic leukaemia · B cell lymphoma · multiple myeloma · genetic engineering · metabolic dysfunction · therapeutic efficacy

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Pepkio Research Index (PRI). Topics and Trends in Most Cited CRISPR and Genetic Engineering Papers, Class of 2026. https://pri.pepkio.com/top-papers/crispr-and-genetic-engineering/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459