Rapid in silico directed evolution by a protein language model with EVOLVEpro
#2PRI RANKED
Most Cited Paper
in CRISPR and Genetic Engineering
18 Months Post-Publication
Class of 2026
“Rapid in silico directed evolution by a protein language model with EVOLVEpro”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/crispr-and-genetic-engineering/2026/
Topics
EVOLVEpro · Protein language model · Directed evolution · few-shot active learning · Fitness landscape · multiproperty optimization · Zero-shot prediction · RNA production · Genome editing · antibody binding · regression models · AI-guided protein engineering · protein activity prediction · local maxima traps · AI-guided protein engineering
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Pepkio Research Index (PRI). Topics and Trends in Most Cited CRISPR and Genetic Engineering Papers, Class of 2026. https://pri.pepkio.com/top-papers/crispr-and-genetic-engineering/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459