Ligand binding initiates single-molecule integrin conformational activation
Most Cited Paper
in Cell Adhesion Molecules Research
18 Months Post-Publication
Class of 2026
“Ligand binding initiates single-molecule integrin conformational activation”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026/
Topics
Integrin activation · single-molecule fluorescence dynamics · bent-closed integrin conformation · leg extension · headpiece opening · high-affinity integrin conformation · extended-closed integrin conformation · extended-open integrin conformation · ligand binding · ligand dissociation pathway · talin · integrin β-subunit cytoplasmic domain · actin cytoskeleton linkage · outside-in signaling · inside-out signaling · tensile force transmission · ligand-integrin-talin-actin cytoskeleton complex · Cell migration · cell adhesiveness
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Cell Adhesion Molecules Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/cell-adhesion-molecules-research/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459