Tumour evolution and microenvironment interactions in 2D and 3D space

Topics

Tumor evolution · Tumor microenvironment · Spatial transcriptomics · Visium spatial transcriptomics · Single-nucleus RNA sequencing · CODEX (co-detection by indexing) · tumour microregions · spatial subclones · Intratumour heterogeneity · Copy number variation · Somatic mutations · oncogenic activity · metabolic activity · antigen presentation · Immune cell infiltration · macrophages · tumour boundaries · immune hot neighbourhoods · immune cold neighbourhoods · immune exhaustion · 3D tumour reconstruction · serial section co-registration · stromal components · cancer cell clusters · Subclonal expansion · spatial tumour heterogeneity · unsupervised deep-learning algorithm · multimodal data integration · Metastasis · tumour spatial organization · leading edge biology · tumour habitats · Clonal evolution