Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment
#3PRI RANKED
Most Cited Paper
in Cancer Cells and Metastasis
18 Months Post-Publication
Class of 2026
“Tumor-associated macrophages restrict CD8+ T cell function through collagen deposition and metabolic reprogramming of the breast cancer microenvironment”
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Topics
Tumor-associated macrophages · CD8+ T cells · Extracellular matrix remodeling · metabolic reprogramming · breast cancer microenvironment · T cell dysfunction · Extracellular matrix remodeling · Immunosuppressive tumor microenvironment · macrophage-T cell interaction · Tumor stroma · metabolic competition · Immune evasion · collagen-mediated immune exclusion
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer Cells and Metastasis Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-cells-and-metastasis/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459