Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo

🏆 Top 20📊 OpenAlex

Most Cited Paper

in Cancer Cells and Metastasis

18 Months Post-Publication

Class of 2026

“Spatiotemporally resolved colorectal oncogenesis in mini-colons ex vivo”

AuthorsL Francisco Lorenzo-Martín, Tania Hübscher et al.

L. Francisco Lorenzo‐Martín, Matthias P. Lütolf

JournalNature

École Polytechnique Fédérale de Lausanne (EPFL)

Citations65

DOI10.1038/s41586-024-07330-2

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Topics

Tumor organoids · Tumor organoids · Tumor progression · tumorigenesis ex vivo · microfabrication · optogenetic control · tissue engineering · blue-light exposure · oncogenic activation · single-cell resolution · real-time tracking · Tumor heterogeneity · Inter-patient heterogeneity · Colorectal cancer · topobiological complexity · oncogenic transformation · spatiotemporal control · cell-intrinsic determinants · cell-extrinsic parameters · Tumor progression

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Cancer Cells and Metastasis Papers, Class of 2026. https://pri.pepkio.com/top-papers/cancer-cells-and-metastasis/2026. Accessed 2026-10-24.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459