Establishing a synthetic orthogonal replication system enables accelerated evolution in <i>E. coli</i>
Most Cited Paper
in Bacterial Genetics and Biotechnology
18 Months Post-Publication
Class of 2026
“Establishing a synthetic orthogonal replication system enables accelerated evolution in <i>E. coli</i>”
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Topics
Orthogonal replication · Orthogonal replication · Orthogonal replication · Continuous evolution · mutagenesis rate elevation · tigecycline resistance evolution · GFP fluorescence evolution · Escherichia coli · mutant O-DNAPs · host polymerase orthogonality · replicon cargo capacity · mutation rate engineering · Directed evolution · synthetic biology · selective replication
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Bacterial Genetics and Biotechnology Papers, Class of 2026. https://pri.pepkio.com/top-papers/bacterial-genetics-and-biotechnology/2026. Accessed 2026-10-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459