Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria
Most Cited Paper
in Antimicrobial Resistance in Staphylococcus
18 Months Post-Publication
Class of 2026
“Biguanide-Vancomycin Conjugates are Effective Broad-Spectrum Antibiotics against Actively Growing and Biofilm-Associated Gram-Positive and Gram-Negative ESKAPE Pathogens and Mycobacteria”
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pri.pepkio.com
Topics
biguanide-vancomycin conjugates · V–C6–Bg-PhCl · ESKAPE pathogens · vancomycin-resistant enterococcus · mycobacteria · biofilm-associated bacteria · Gram-negative bacteria · Gram-positive bacteria · cell wall synthesis inhibition · biguanide association with cell-surface anions · vancomycin binding sites · oritavancin · antibiotic-resistant infections · Bacterial persisters · biguanidinylation · broad-spectrum antibiotics · Persistent infections
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Antimicrobial Resistance in Staphylococcus Papers, Class of 2026. https://pri.pepkio.com/top-papers/antimicrobial-resistance-in-staphylococcus/2026. Accessed 2026-09-03. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459