Development and validation of animal variant classification guidelines to objectively evaluate genetic variant pathogenicity in domestic animals

Topics

Animal variant classification guidelines · Animal variant classification guidelines · genetic variant pathogenicity · domestic animals · Mendelian disorders · ACMG guidelines · ACMG guidelines · variant classification criteria · in silico variant effect predictor tools · disease-associated variants · DNA test validity · breeding decisions · benchmarking datasets · pathogenic variant classification · cats · population-level genetic assessment · individual-level genetic assessment · standardized pathogenicity criteria · reproducibility validation