An Engineered Bionic Nanoparticle Sponge as a Cytokine Trap and Reactive Oxygen Species Scavenger to Relieve Disc Degeneration and Discogenic Pain
Most Cited Paper
in Anesthesia and Pain Management
18 Months Post-Publication
Class of 2026
“An Engineered Bionic Nanoparticle Sponge as a Cytokine Trap and Reactive Oxygen Species Scavenger to Relieve Disc Degeneration and Discogenic Pain”
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Topics
MnO2@TMNP nanoparticle · TrkA-overexpressed macrophage cell membrane · cytokine trap · reactive oxygen species scavenging · intervertebral disc degeneration · discogenic pain · M1 macrophage polarization · nucleus pulposus cells · nerve growth factor binding · inflammation-induced apoptosis · matrix degradation · nerve ingrowth · macrophage-targeted delivery · calcitonin gene-related peptide · substance P · dorsal root ganglion · GFAP signaling · c-FOS signaling · mechanical and thermal hyperalgesia · inflammatory immune microenvironment
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Anesthesia and Pain Management Papers, Class of 2026. https://pri.pepkio.com/top-papers/anesthesia-and-pain-management/2026. Accessed 2026-08-20. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459