Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies
Most Cited Paper
in Alzheimer's disease research and treatments
18 Months Post-Publication
Class of 2026
“Restoring hippocampal glucose metabolism rescues cognition across Alzheimer’s disease pathologies”
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pri.pepkio.com
Topics
indoleamine-2,3-dioxygenase 1 (IDO1) · kynurenine (KYN) · tryptophan metabolism · astrocyte metabolism · hippocampal glucose metabolism · aryl hydrocarbon receptor · monocarboxylate transporter · Amyloid β oligomers · Tau oligomers · glycolysis suppression · hippocampal long-term potentiation · lactate shuttle · astrocyte-neuron metabolic coupling · IDO1 inhibition · Alzheimer's disease mouse models · Cerebral glucose metabolism · AD proteomic studies · IDO1 inhibitor repurposing · astrocytic lactate production · neuronal lactate uptake
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Alzheimer's disease research and treatments Papers, Class of 2026. https://pri.pepkio.com/top-papers/alzheimer-s-disease-research-and-treatments/2026. Accessed 2026-07-24. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459