Multi-pass, single-molecule nanopore reading of long protein strands

Topics

Nanopore sequencing · Single-molecule protein sequencing · ClpX unfoldase · CsgG nanopore · protein translocation · two-residue stepping mechanism · Single-molecule protein sequencing · post-translational modification mapping · phosphorylation detection · multi-pass protein rereading · Single-molecule protein sequencing · biophysical signal modeling · residue volume and charge · full-length proteoform analysis · protein domain unfolding · single-amino-acid substitution sequencing · electrophoretic protein threading · unfoldase motor mechanism