Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation
Most Cited Paper
in Adipose Tissue and Metabolism
18 Months Post-Publication
Class of 2026
“Hypoxia induces mitochondrial protein lactylation to limit oxidative phosphorylation”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026/
Topics
mitochondrial protein lactylation · Oxidative phosphorylation · physiological hypoxia · AARS2 · AARS2 · lysine lactyltransferase · PHD2 · proline 377 hydroxylation · proteasomal degradation · PDHA1 · pyruvate dehydrogenase complex · PDHA1 lysine 336 lactylation · CPT2 · carnitine palmitoyltransferase 2 · CPT2 lysine 457/458 lactylation · SIRT3 · acetyl-CoA influx · Fatty acid β-oxidation · lactate oxidation · exercise-induced hypoxia
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026. https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459