Inhibition of IL-11 signalling extends mammalian healthspan and lifespan
#4PRI RANKED
Most Cited Paper
in Adipose Tissue and Metabolism
18 Months Post-Publication
Class of 2026
“Inhibition of IL-11 signalling extends mammalian healthspan and lifespan”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026/
Topics
IL-11 · IL-11 signalling · IL11ra1 · ERK-AMPK-mTORC1 axis · metabolic decline · multi-morbidity · frailty · Aging biomarker · anti-IL-11 therapy · genetic deletion · lifespan extension · Healthspan · pro-inflammatory cytokine · IL-6 family · muscle function · fibrotic lung disease · Aging · tissue-level ageing · organismal-level ageing
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Adipose Tissue and Metabolism Papers, Class of 2026. https://pri.pepkio.com/top-papers/adipose-tissue-and-metabolism/2026. Accessed 2026-07-22. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459