RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax
Most Cited Paper
in Acute Myeloid Leukemia Research
18 Months Post-Publication
Class of 2026
“RAS-mutant leukaemia stem cells drive clinical resistance to venetoclax”
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Topics
RAS mutations · Acute myeloid leukemia (AML) · leukaemia stem cells · Venetoclax · Venetoclax · granulocyte–monocyte progenitors · monocytic disease · Clonal evolution · BCL2 family gene expression · relapsed/refractory disease · Driver mutations · temporal acquisition patterns · committed progenitors · haematopoietic hierarchy · Therapy resistance · myelomonocytic lineage · LSC target cell restriction
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026. Accessed 2026-07-31. Methodology Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459