Analysis of somatic mutations in whole blood from 200,618 individuals identifies pervasive positive selection and novel drivers of clonal hematopoiesis

Topics

Clonal hematopoiesis · somatic mutations · positive selection · UK Biobank · Whole exome sequencing · ZBTB33 · ZNF318 · ZNF234 · SPRED2 · SH2B3 · SRCAP · SIK3 · SRSF1 · CHEK2 · CCDC115 · CCL22 · BAX · YLPM1 · MYD88 · MTA2

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Pepkio Research Index (PRI). Topics and Trends in Most Cited Acute Myeloid Leukemia Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/acute-myeloid-leukemia-research/2026. Accessed 2026-07-31.

Methodology
Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459