Metformin targets mitochondrial complex I to lower blood glucose levels
Most Cited Paper
in Pancreatic function and diabetes
18 Months Post-Publication
Class of 2026
“Metformin targets mitochondrial complex I to lower blood glucose levels”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/pancreatic-function-and-diabetes/2026/
Topics
metformin · mitochondrial complex I · electron transport chain · Glucose-lowering therapy · NDI1 · Saccharomyces cerevisiae internal alternative NADH dehydrogenase · transgenic mice · acute oral administration · antidiabetic mechanism · pharmacologic complex I inhibition · High-fat diet · NADH dehydrogenase · Metabolic homeostasis · mitochondrial respiration
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Pancreatic function and diabetes Papers, Class of 2026. https://pri.pepkio.com/top-papers/pancreatic-function-and-diabetes/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459