Dapagliflozin mitigates cellular stress and inflammation through PI3K/AKT pathway modulation in cardiomyocytes, aortic endothelial cells, and stem cell-derived β cells
Topics
dapagliflozin · SGLT2 inhibitors · PI3K/AKT pathway · cardiomyocytes · aortic endothelial cells · Stem cell-derived islets · isoproterenol-induced hypertrophy · reactive oxygen species · NHE1 · GLUT1 · eNOS · TNFα-induced inflammation · MAFA · NRF2 · NLRP3 inflammasome · GRP78 · MAPK activation · Cardioprotection · endothelial function · Beta cell function
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Pancreatic function and diabetes Papers, Class of 2026. https://pri.pepkio.com/top-papers/pancreatic-function-and-diabetes/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459

