SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization
Most Cited Paper
in Pancreatic function and diabetes
18 Months Post-Publication
Class of 2026
“SGLT2 inhibitors ameliorate NAFLD in mice via downregulating PFKFB3, suppressing glycolysis and modulating macrophage polarization”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/pancreatic-function-and-diabetes/2026/
Topics
SGLT2 inhibitors · NAFLD · PFKFB3 · Glycolysis · macrophage polarization · dapagliflozin · canagliflozin · Diabetic mouse models · western diet-induced NAFLD · hepatic steatosis · Hepatic fibrosis · M1 macrophage · M2 macrophages · bone marrow-derived macrophages · metabolic reprogramming · RNA sequencing · Seahorse analysis · macrophage-hepatocyte co-culture · lipogenesis · pro-inflammatory cytokines
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Pancreatic function and diabetes Papers, Class of 2026. https://pri.pepkio.com/top-papers/pancreatic-function-and-diabetes/2026. Accessed 2026-07-21. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459