Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy
Most Cited Paper
in Epigenetics and DNA Methylation
18 Months Post-Publication
Class of 2026
“Epigenetic regulators of clonal hematopoiesis control CD8 T cell stemness during immunotherapy”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/epigenetics-and-dna-methylation/2026/
Topics
Clonal hematopoiesis · T cell stemness · T cell exhaustion · progenitor-exhausted T cells (Tpex) · Dnmt3a · Tet2 · Asxl1 · Immune checkpoint blockade · anti-PD-L1 · chronic antigen exposure · H2AK119ub · polycomb group-repressive deubiquitinase pathway · T cell self-renewal · CD8 T cell differentiation · Epigenetic modification · Anti-tumor immunity · tumor control
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Epigenetics and DNA Methylation Papers, Class of 2026. https://pri.pepkio.com/top-papers/epigenetics-and-dna-methylation/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459