DPF2 reads histone lactylation to drive transcription and tumorigenesis
Most Cited Paper
in Epigenetics and DNA Methylation
18 Months Post-Publication
Class of 2026
“DPF2 reads histone lactylation to drive transcription and tumorigenesis”
A research intelligence initiative by Pepkio
pri.pepkio.com/top-papers/epigenetics-and-dna-methylation/2026/
Topics
lysine lactylation · H3K14la · histone lactylation · DPF2 · cervical cancer · lactate accumulation · Metabolic reprogramming · multivalent photoaffinity probe · quantitative proteomics · Epigenetic reader · CUT&Tag · oncogenic gene transcription · structure-guided mutation · DPF2-H3K14la interaction · Epigenetic reader · Epigenetic reader · transcriptional regulation · cell survival
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Pepkio Research Index (PRI). Topics and Trends in Most Cited Epigenetics and DNA Methylation Papers, Class of 2026. https://pri.pepkio.com/top-papers/epigenetics-and-dna-methylation/2026. Accessed 2026-07-20. Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459