# Optimisation of dose level and vaccination schedule for the VLA15 Lyme borreliosis vaccine candidate among healthy adults: two randomised, observer-blind, placebo-controlled, multicentre, phase 2 studies

*PRI Rank #10 · Topics and Trends in Most Cited Vector-borne infectious diseases Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/vector-borne-infectious-diseases/2026/rank-10*

| Field | Value |
| --- | --- |
| Rank | #10 |
| 18m citations | 22 |
| Journal | The Lancet Infectious Diseases |
| Year | 2024 |
| DOI | 10.1016/s1473-3099(24)00175-0 |
| Corresponding authors | Susanne Eder-Lingelbach |
| Institution | Valneva Austria, Austria |

**Ranking page:** [Topics and Trends in Most Cited Vector-borne infectious diseases Papers, Class of 2026](https://pri.pepkio.com/top-papers/vector-borne-infectious-diseases/2026)

**Paper link:** [10.1016/s1473-3099(24)00175-0](https://doi.org/10.1016/s1473-3099(24)00175-0)

## Topics

VLA15 · Lyme disease vaccine · dose optimization · vaccination schedule · phase 2 trial · observer-blind design · placebo-controlled study · Healthy adults · Multicentre trial · immunogenicity · safety endpoints · dose-response relationship · prime-boost regimen · antibody titers · OspA · Borrelia burgdorferi · vaccine efficacy · adverse events

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Vector-borne infectious diseases Papers, Class of 2026. https://pri.pepkio.com/top-papers/vector-borne-infectious-diseases/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```