# Type I IFN-mediated NET release promotes Mycobacterium tuberculosis replication and is associated with granuloma caseation

*PRI Rank #8 · Topics and Trends in Most Cited Tuberculosis Research and Epidemiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/tuberculosis-research-and-epidemiology/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 48 |
| Journal | Cell Host & Microbe |
| Year | 2024 |
| DOI | 10.1016/j.chom.2024.11.008 |
| Corresponding authors | Christina L. Stallings |
| Institution | Washington University School of Medicine, United States |

**Ranking page:** [Topics and Trends in Most Cited Tuberculosis Research and Epidemiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/tuberculosis-research-and-epidemiology/2026)

**Paper link:** [10.1016/j.chom.2024.11.008](https://doi.org/10.1016/j.chom.2024.11.008)

## Topics

neutrophil extracellular traps · NETs · Mycobacterium tuberculosis · PAD4 · histone citrullination · Type I interferon · chromatin decondensation · granuloma necrosis · nonhuman primate granulomas · neutrophil viability · plasma membrane integrity · chromatin-containing vesicles · granuloma necrosis · Mtb replication · tuberculosis pathogenesis

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Tuberculosis Research and Epidemiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/tuberculosis-research-and-epidemiology/2026. Accessed 2026-07-24.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```