# Lymphatic-localized Treg-mregDC crosstalk limits antigen trafficking and restrains anti-tumor immunity

*PRI Rank #16 · Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026/rank-16*

| Field | Value |
| --- | --- |
| Rank | #16 |
| 18m citations | 79 |
| Journal | Cancer Cell |
| Year | 2024 |
| DOI | 10.1016/j.ccell.2024.06.014 |
| Corresponding authors | Siyuan You |
| Institution | Xiamen University, China |

**Ranking page:** [Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026](https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026)

**Paper link:** [10.1016/j.ccell.2024.06.014](https://doi.org/10.1016/j.ccell.2024.06.014)

## Topics

lymphatic-localized · Regulatory T cells · mregDC · antigen trafficking · Antitumor immunity · Regulatory T cells · migratory regulatory dendritic cells · Tumor microenvironment · lymphatic system · Immunosuppression · dendritic cell migration · T cell-DC crosstalk · tumor antigen presentation · Lymph nodes · Cancer immunology

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026. https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```