# Xist ribonucleoproteins promote female sex-biased autoimmunity

*PRI Rank #1 · Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 133 |
| Journal | Cell |
| Year | 2024 |
| DOI | 10.1016/j.cell.2023.12.037 |
| Corresponding authors | Howard Y. Chang |
| Institution | Stanford University, United States |

**Ranking page:** [Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026](https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026)

**Paper link:** [10.1016/j.cell.2023.12.037](https://doi.org/10.1016/j.cell.2023.12.037)

## Topics

Xist long non-coding RNA · X chromosome inactivation · Sex-biased autoimmunity · Xist ribonucleoprotein complex · autoantibodies · transgenic Xist expression · non-silencing Xist · SJL/J mice · pristane-induced lupus model · T cell reprogramming · B cell reprogramming · chromatin state changes · Xist ribonucleoprotein complex · XX sex chromosome complement · Sex-biased autoimmunity · lncRNA scaffold

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited T-cell and B-cell Immunology Papers, Class of 2026. https://pri.pepkio.com/top-papers/t-cell-and-b-cell-immunology/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```