# Signatures of metabolic diseases on spermatogenesis and testicular metabolism

*PRI Rank #4 · Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026/rank-4*

| Field | Value |
| --- | --- |
| Rank | #4 |
| 18m citations | 26 |
| Journal | Nature Reviews Urology |
| Year | 2024 |
| DOI | 10.1038/s41585-024-00866-y |
| Corresponding authors | Marco G. Alves |
| Institution | University of Porto, Portugal |

**Ranking page:** [Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026](https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026)

**Paper link:** [10.1038/s41585-024-00866-y](https://doi.org/10.1038/s41585-024-00866-y)

## Topics

metabolic diseases · Spermatogenesis · testicular metabolism · male fertility · Sperm quality · metabolic dysfunction · germ cell development · Testicular function · reproductive endocrinology · diabetes · obesity · metabolic syndrome · hormonal regulation · energy metabolism · oxidative stress

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026. https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```