# Bi-allelic variants in <i>DNAH3</i> cause male infertility with asthenoteratozoospermia in humans and mice

*PRI Rank #20 · Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 20 |
| Journal | Human Reproduction Open |
| Year | 2024 |
| DOI | 10.1093/hropen/hoae003 |
| Corresponding authors | Yanwei Sha, Lingbo Wang, Wenbin He |
| Institution | Hunan Guangxiu Hospital, China |

**Ranking page:** [Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026](https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026)

**Paper link:** [10.1093/hropen/hoae003](https://doi.org/10.1093/hropen/hoae003)

## Topics

DNAH3 · asthenoteratozoospermia · male infertility · bi-allelic variants · Whole exome sequencing · Dnah3 knockout mice · central pair microtubules · inner dynein arms · mitochondrial sheath · fibrous sheath · flagellar morphology · transmission electron microscopy · Computer-assisted sperm analysis · Intracytoplasmic sperm injection · Asthenozoospermia · haematoxylin and eosin staining · immunostaining

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026. https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```