# Stem Leydig cells support macrophage immunological homeostasis through mitochondrial transfer in mice

*PRI Rank #18 · Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026/rank-18*

| Field | Value |
| --- | --- |
| Rank | #18 |
| 18m citations | 20 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-46190-2 |
| Corresponding authors | Xuetao Shi, Chunhua Deng, Min Zhang |
| Institution | Sun Yat-sen University, China |

**Ranking page:** [Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026](https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026)

**Paper link:** [10.1038/s41467-024-46190-2](https://doi.org/10.1038/s41467-024-46190-2)

## Topics

stem Leydig cells · macrophages · mitochondrial transfer · male hypogonadism · Ischemia-reperfusion injury · Testosterone production · male fertility · Reactive oxygen species · TRPM7 · TRPM7 · testicular mesenchymal stromal cells · inflammatory cascades · Testicular aging · cell transplantation therapy · immunoregulation · Testicular function

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026. https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```