# Damage to Mitochondria During the Cryopreservation, Causing <scp>ROS</scp> Leakage, Leading to Oxidative Stress and Decreased Quality of Ram Sperm

*PRI Rank #13 · Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026/rank-13*

| Field | Value |
| --- | --- |
| Rank | #13 |
| 18m citations | 22 |
| Journal | Reproduction in Domestic Animals |
| Year | 2024 |
| DOI | 10.1111/rda.14737 |
| Corresponding authors | Jian Wang, Yongjun Li |
| Institution | Yangzhou University, China |

**Ranking page:** [Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026](https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026)

**Paper link:** [10.1111/rda.14737](https://doi.org/10.1111/rda.14737)

## Topics

ram sperm cryopreservation · Sperm mitochondrial dysfunction · Reactive oxygen species · oxidative stress · Mitochondrial membrane potential · Adenosine triphosphate · NDUFV2 · SDHA · CYC1 · COXIV · Malondialdehyde · Phosphatidylserine externalization · mtDNA copy number · Bax · Caspase-3 · Caspase-8 · Cytochrome C · electron transport chain · sperm apoptosis · Acrosome integrity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Sperm and Testicular Function Papers, Class of 2026. https://pri.pepkio.com/top-papers/sperm-and-testicular-function/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```