# Single-cell transcriptomics across 2,534 microbial species reveals functional heterogeneity in the rumen microbiome

*PRI Rank #1 · Topics and Trends in Most Cited Ruminant Nutrition and Digestive Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/ruminant-nutrition-and-digestive-physiology/2026/rank-1*

| Field | Value |
| --- | --- |
| Rank | #1 |
| 18m citations | 48 |
| Journal | Nature Microbiology |
| Year | 2024 |
| DOI | 10.1038/s41564-024-01723-9 |
| Corresponding authors | Yongcheng Wang, Hui‐Zeng Sun |
| Institution | Zhejiang University, China |

**Ranking page:** [Topics and Trends in Most Cited Ruminant Nutrition and Digestive Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/ruminant-nutrition-and-digestive-physiology/2026)

**Paper link:** [10.1038/s41564-024-01723-9](https://doi.org/10.1038/s41564-024-01723-9)

## Topics

Single-cell RNA sequencing · Rumen microbiota · Microbial diversity · functional heterogeneity · Microbial transcriptomics · rumen microbial ecology · Single-cell RNA sequencing · Microbial transcriptomics · species-level resolution · microbial community function · Rumen fermentation · microbial metabolic activity · cell-to-cell variation · Microbial transcriptomics · ruminant digestion

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Ruminant Nutrition and Digestive Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/ruminant-nutrition-and-digestive-physiology/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```