# Prediction of m6A and m5C at single-molecule resolution reveals a transcriptome-wide co-occurrence of RNA modifications

*PRI Rank #6 · Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026/rank-6*

| Field | Value |
| --- | --- |
| Rank | #6 |
| 18m citations | 74 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-47953-7 |
| Corresponding authors | Nikolay E. Shirokikh, Eduardo Eyras |
| Institution | Australian National University, Australia |

**Ranking page:** [Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026](https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026)

**Paper link:** [10.1038/s41467-024-47953-7](https://doi.org/10.1038/s41467-024-47953-7)

## Topics

CHEUI · m6A · m6A · 5-methylcytosine (m5C) · 5-methylcytosine (m5C) · epitranscriptomics · single-molecule resolution · nanopore direct RNA sequencing · ionic current signal · RNA modification stoichiometry · differential methylation · co-occurrence of RNA modifications · transcript-site prediction · synthetic RNA standards · multi-modification detection

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```