# IGF2BP3 promotes mRNA degradation through internal m7G modification

*PRI Rank #17 · Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026/rank-17*

| Field | Value |
| --- | --- |
| Rank | #17 |
| 18m citations | 50 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-51634-w |
| Corresponding authors | Chuan He |
| Institution | The University of Chicago, United States |

**Ranking page:** [Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026](https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026)

**Paper link:** [10.1038/s41467-024-51634-w](https://doi.org/10.1038/s41467-024-51634-w)

## Topics

IGF2BP3 · mRNA degradation · N7-methylguanosine (m7G) · METTL1 · IGF2BP family proteins · IGF2BP1 · IGF2BP2 · m6A · TP53 transcript · N7-methylguanosine (m7G) · glioblastoma · dCas13b-guided system · site-specific m7G targeting · mRNA stability · mRNA stability · chemosensitivity · cancer progression · m6A reader proteins

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA modifications and cancer Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-modifications-and-cancer/2026. Accessed 2026-07-22.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```