# Precision drug delivery to the central nervous system using engineered nanoparticles

*PRI Rank #19 · Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 82 |
| Journal | Nature Reviews Materials |
| Year | 2024 |
| DOI | 10.1038/s41578-024-00695-w |
| Corresponding authors | Jingjing Gao, Jeffrey M. Karp, Nitin Joshi |
| Institution | University of Massachusetts, United States |

**Ranking page:** [Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026](https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026)

**Paper link:** [10.1038/s41578-024-00695-w](https://doi.org/10.1038/s41578-024-00695-w)

## Topics

precision drug delivery · central nervous system · engineered nanoparticles · Blood-brain barrier · Targeted drug delivery · Nanoparticle design · CNS drug delivery · therapeutic nanoparticles · CNS drug delivery · nanomedicine

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```