# Enhancing in situ cancer vaccines using delivery technologies

*PRI Rank #11 · Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 101 |
| Journal | Nature Reviews Drug Discovery |
| Year | 2024 |
| DOI | 10.1038/s41573-024-00974-9 |
| Corresponding authors | Drew Weissman, Michael J. Mitchell |
| Institution | University of Pennsylvania, United States |

**Ranking page:** [Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026](https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026)

**Paper link:** [10.1038/s41573-024-00974-9](https://doi.org/10.1038/s41573-024-00974-9)

## Topics

in situ cancer vaccines · Drug delivery systems · immunotherapy · tumor microenvironment · antigen presentation · Dendritic cell maturation · immune checkpoint inhibitors · nanoparticle delivery · Immunogenicity · Cytotoxic T lymphocytes · abscopal effect · intratumoral injection · biomaterials · cancer immunotherapy · antitumor immunity

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited RNA Interference and Gene Delivery Papers, Class of 2026. https://pri.pepkio.com/top-papers/rna-interference-and-gene-delivery/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```