# A deep learning system for predicting time to progression of diabetic retinopathy

*PRI Rank #2 · Topics and Trends in Most Cited Retinal Diseases and Treatments Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/retinal-diseases-and-treatments/2026/rank-2*

| Field | Value |
| --- | --- |
| Rank | #2 |
| 18m citations | 150 |
| Journal | Nature Medicine |
| Year | 2024 |
| DOI | 10.1038/s41591-023-02702-z |
| Corresponding authors | Bin Sheng, Huating Li, Tien Yin Wong, Weiping Jia |
| Institution | Shanghai Jiao Tong University, China |

**Ranking page:** [Topics and Trends in Most Cited Retinal Diseases and Treatments Papers, Class of 2026](https://pri.pepkio.com/top-papers/retinal-diseases-and-treatments/2026)

**Paper link:** [10.1038/s41591-023-02702-z](https://doi.org/10.1038/s41591-023-02702-z)

## Topics

DeepDR Plus · Deep learning · Diabetic retinopathy prediction · Fundus image · time-to-event prediction · concordance index · integrated Brier score · Screening interval extension · multiethnic dataset · model pretraining · Diabetic retinopathy · Real-world evidence · Risk stratification · survival analysis in ophthalmology · Screening interval extension · delayed detection rate · diabetes screening workflow integration · individualized risk prediction

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Retinal Diseases and Treatments Papers, Class of 2026. https://pri.pepkio.com/top-papers/retinal-diseases-and-treatments/2026. Accessed 2026-07-14.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```