# Curcumin mitigates polycystic ovary syndrome in mice by suppressing TLR4/MyD88/NF-κB signaling pathway activation and reducing intestinal mucosal permeability

*PRI Rank #12 · Topics and Trends in Most Cited Reproductive Physiology in Livestock Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/reproductive-physiology-in-livestock/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 18 |
| Journal | Scientific Reports |
| Year | 2024 |
| DOI | 10.1038/s41598-024-81034-5 |
| Corresponding authors | Qin Wan, Zhen Wang |
| Institution | The people's Hospital of Leshan, China |

**Ranking page:** [Topics and Trends in Most Cited Reproductive Physiology in Livestock Papers, Class of 2026](https://pri.pepkio.com/top-papers/reproductive-physiology-in-livestock/2026)

**Paper link:** [10.1038/s41598-024-81034-5](https://doi.org/10.1038/s41598-024-81034-5)

## Topics

curcumin · polycystic ovary syndrome · TLR4/MyD88/NF-κB signaling pathway · Intestinal permeability · dehydroepiandrosterone · C57BL/6J mice · chronic inflammation · tight junction proteins · ZO-1 · occludin · Lipopolysaccharide · testosterone · LH · estradiol · insulin sensitivity · IL-17A · IL-6 · TNF · IL-10 · intestinal mucosal barrier

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Reproductive Physiology in Livestock Papers, Class of 2026. https://pri.pepkio.com/top-papers/reproductive-physiology-in-livestock/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```