# Cellular atlas of the human ovary using morphologically guided spatial transcriptomics and single-cell sequencing

*PRI Rank #12 · Topics and Trends in Most Cited Reproductive Biology and Fertility Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/reproductive-biology-and-fertility/2026/rank-12*

| Field | Value |
| --- | --- |
| Rank | #12 |
| 18m citations | 40 |
| Journal | Science Advances |
| Year | 2024 |
| DOI | 10.1126/sciadv.adm7506 |
| Corresponding authors | Andrea Jones, D. Ford Hannum, Jun Z. Li, Ariella Shikanov |
| Institution | University of Michigan, United States |

**Ranking page:** [Topics and Trends in Most Cited Reproductive Biology and Fertility Papers, Class of 2026](https://pri.pepkio.com/top-papers/reproductive-biology-and-fertility/2026)

**Paper link:** [10.1126/sciadv.adm7506](https://doi.org/10.1126/sciadv.adm7506)

## Topics

spatial transcriptomics · Single-cell transcriptomics · human ovary · oocytes · theca cells · Granulosa cells · Follicle development · Ovarian cortex · ovarian medulla · hormone remodeling · extracellular matrix remodeling · immune cell subtypes · morphologically guided sampling · premenopausal donors · oocyte-specific genes · theca-specific genes · granulosa-specific genes · Ovarian cell atlas

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Reproductive Biology and Fertility Papers, Class of 2026. https://pri.pepkio.com/top-papers/reproductive-biology-and-fertility/2026. Accessed 2026-07-17.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```