# Reinforcement of the intestinal mucosal barrier via mucus-penetrating PEGylated bacteria

*PRI Rank #5 · Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 71 |
| Journal | Nature Biomedical Engineering |
| Year | 2024 |
| DOI | 10.1038/s41551-024-01224-4 |
| Corresponding authors | Jinyao Liu |
| Institution | Shanghai Jiao Tong University, China |

**Ranking page:** [Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026](https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026)

**Paper link:** [10.1038/s41551-024-01224-4](https://doi.org/10.1038/s41551-024-01224-4)

## Topics

Intestinal barrier function · Mucus penetration · PEGylated bacteria · PEGylation · Mucus penetration · barrier reinforcement · Probiotic engineering · mucosal delivery · Gut microbiota modulation

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026. https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```