# A Gram-negative-selective antibiotic that spares the gut microbiome

*PRI Rank #3 · Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026/rank-3*

| Field | Value |
| --- | --- |
| Rank | #3 |
| 18m citations | 87 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07502-0 |
| Corresponding authors | Paul J. Hergenrother |
| Institution | University of Illinois at Urbana-Champaign, United States |

**Ranking page:** [Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026](https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026)

**Paper link:** [10.1038/s41586-024-07502-0](https://doi.org/10.1038/s41586-024-07502-0)

## Topics

Gram-negative-selective antibiotic · gut microbiome sparing · selective antimicrobial activity · Gram-negative bacteria · Microbiota preservation · antibiotic selectivity · narrow-spectrum antibiotic

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026. https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```