# Chitosan and its derivatives: A novel approach to gut microbiota modulation and immune system enhancement

*PRI Rank #11 · Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026/rank-11*

| Field | Value |
| --- | --- |
| Rank | #11 |
| 18m citations | 51 |
| Journal | International Journal of Biological Macromolecules |
| Year | 2024 |
| DOI | 10.1016/j.ijbiomac.2024.138633 |
| Corresponding authors | Great Iruoghene Edo |
| Institution | Delta State University of Science and Technology, Nigeria |

**Ranking page:** [Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026](https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026)

**Paper link:** [10.1016/j.ijbiomac.2024.138633](https://doi.org/10.1016/j.ijbiomac.2024.138633)

## Topics

Chitosan · Chitosan · Gut microbiota modulation · immune system enhancement · prebiotic activity · Short-chain fatty acids · Intestinal barrier function · Immunomodulation · Antimicrobial activity · Beneficial microorganisms · Gut microbiota composition · inflammatory response · mucosal immunity · polysaccharide structure

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Probiotics and Fermented Foods Papers, Class of 2026. https://pri.pepkio.com/top-papers/probiotics-and-fermented-foods/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```