# Placental IGFBP1 levels during early pregnancy and the risk of insulin resistance and gestational diabetes

*PRI Rank #20 · Topics and Trends in Most Cited Pregnancy and preeclampsia studies Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/pregnancy-and-preeclampsia-studies/2026/rank-20*

| Field | Value |
| --- | --- |
| Rank | #20 |
| 18m citations | 28 |
| Journal | Nature Medicine |
| Year | 2024 |
| DOI | 10.1038/s41591-024-02936-5 |
| Corresponding authors | Marie‐France Hivert |
| Institution | Harvard Pilgrim Health Care Institute, United States |

**Ranking page:** [Topics and Trends in Most Cited Pregnancy and preeclampsia studies Papers, Class of 2026](https://pri.pepkio.com/top-papers/pregnancy-and-preeclampsia-studies/2026)

**Paper link:** [10.1038/s41591-024-02936-5](https://doi.org/10.1038/s41591-024-02936-5)

## Topics

IGFBP1 · insulin resistance · Gestational diabetes mellitus · insulin sensitivity · placental transcriptomics · circulating IGFBP1 protein levels · decidual source · early pregnancy biomarker · GDM prediction · glycemic physiology of pregnancy · placental IGFBP1 deficiency · 26 weeks gestation · postpartum decline · IGFBP1

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Pregnancy and preeclampsia studies Papers, Class of 2026. https://pri.pepkio.com/top-papers/pregnancy-and-preeclampsia-studies/2026. Accessed 2026-07-21.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```