# Metabolomics and transcriptomics analysis revealed the response mechanism of alfalfa to combined cold and saline‐alkali stress

*PRI Rank #5 · Topics and Trends in Most Cited Plant Stress Responses and Tolerance Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/plant-stress-responses-and-tolerance/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 69 |
| Journal | The Plant Journal |
| Year | 2024 |
| DOI | 10.1111/tpj.16896 |
| Corresponding authors | Changhong Guo |
| Institution | Harbin Normal University, China |

**Ranking page:** [Topics and Trends in Most Cited Plant Stress Responses and Tolerance Papers, Class of 2026](https://pri.pepkio.com/top-papers/plant-stress-responses-and-tolerance/2026)

**Paper link:** [10.1111/tpj.16896](https://doi.org/10.1111/tpj.16896)

## Topics

combined cold and saline-alkali stress · alfalfa (Medicago sativa L.) · Zhaodong (ZD) variety · Blue Moon (BM) variety · Metabolomics · Transcriptomics · tricarboxylic acid cycle · jasmonic acid · flavonoid biosynthesis pathway · weighted gene co-expression network analysis · MsMYB12 gene · MsFLS13 gene · flavonol accumulation · antioxidant capacity · RNA sequencing · promoter binding · stress tolerance mechanisms

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Plant Stress Responses and Tolerance Papers, Class of 2026. https://pri.pepkio.com/top-papers/plant-stress-responses-and-tolerance/2026. Accessed 2026-10-28.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```