# Physiological and transcriptomic analysis provides new insights into osmoregulation mechanism of Ruditapes philippinarum under low and high salinity stress

*PRI Rank #9 · Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026/rank-9*

| Field | Value |
| --- | --- |
| Rank | #9 |
| 18m citations | 28 |
| Journal | The Science of The Total Environment |
| Year | 2024 |
| DOI | 10.1016/j.scitotenv.2024.173215 |
| Corresponding authors | Hongtao Nie, Zhongming Huo |
| Institution | Dalian Ocean University, China |

**Ranking page:** [Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026](https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026)

**Paper link:** [10.1016/j.scitotenv.2024.173215](https://doi.org/10.1016/j.scitotenv.2024.173215)

## Topics

Ruditapes philippinarum · Osmoregulation · Salinity stress · Salinity stress · Transcriptomics · Physiological responses · Salinity tolerance · Ruditapes philippinarum · Salinity stress · gene expression profiling · Stress response · Marine bivalves · Salinity stress · Salinity stress

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026. https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026. Accessed 2026-10-30.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```