# Oxidative stress induced by hydrogen peroxide disrupts zebrafish visual development by altering apoptosis, antioxidant and estrogen related genes

*PRI Rank #5 · Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026/rank-5*

| Field | Value |
| --- | --- |
| Rank | #5 |
| 18m citations | 32 |
| Journal | Scientific Reports |
| Year | 2024 |
| DOI | 10.1038/s41598-024-64933-5 |
| Corresponding authors | Mitsuyo Kishida, Shao‐Yang Hu |
| Institution | Kumamoto University, Japan |

**Ranking page:** [Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026](https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026)

**Paper link:** [10.1038/s41598-024-64933-5](https://doi.org/10.1038/s41598-024-64933-5)

## Topics

Hydrogen peroxide · zebrafish embryos · visual development · Oxidative stress · eye to body length ratio · optomotor response · retinal apoptosis · Glutathione · pax6α · pax6β · tp53 · casp3 · bax · bcl2α · Superoxide dismutase · cat · gpx1a · estrogen receptors · cyp19a1a · cyp19a1b

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026. https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026. Accessed 2026-10-30.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```