# Metabolic loads and the costs of metazoan reproduction

*PRI Rank #2 · Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026/rank-2*

| Field | Value |
| --- | --- |
| Rank | #2 |
| 18m citations | 38 |
| Journal | Science |
| Year | 2024 |
| DOI | 10.1126/science.adk6772 |
| Corresponding authors | Samuel C. Ginther |
| Institution | Monash University, Australia |

**Ranking page:** [Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026](https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026)

**Paper link:** [10.1126/science.adk6772](https://doi.org/10.1126/science.adk6772)

## Topics

Metabolic stress · energy costs of reproduction · direct reproductive costs · indirect reproductive costs · energy content of offspring · mammals · Ectotherms · viviparity · Oviparity · Ectotherms · Oviparity · lactation · Reproductive investment · Total energy expenditure · bearing costs

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Physiological and biochemical adaptations Papers, Class of 2026. https://pri.pepkio.com/top-papers/physiological-and-biochemical-adaptations/2026. Accessed 2026-10-30.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```