# Control of working memory by phase–amplitude coupling of human hippocampal neurons

*PRI Rank #8 · Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 75 |
| Journal | Nature |
| Year | 2024 |
| DOI | 10.1038/s41586-024-07309-z |
| Corresponding authors | Jonathan Daume, Ueli Rutishauser |
| Institution | Cedars-Sinai Medical Center, United States |

**Ranking page:** [Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026)

**Paper link:** [10.1038/s41586-024-07309-z](https://doi.org/10.1038/s41586-024-07309-z)

## Topics

working memory · phase–amplitude coupling · theta–gamma phase–amplitude coupling · TG-PAC · hippocampal neurons · cognitive control · persistent activity · medial temporal lobe · frontal lobe · Single-neuron recording · PAC neurons · spike timing · frontal theta activity · noise correlations · population code geometry · working memory load · working memory fidelity · multicomponent architecture · top-down control · cross-area coordination

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026. Accessed 2026-07-15.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```