# Complex activity and short-term plasticity of human cerebral organoids reciprocally connected with axons

*PRI Rank #19 · Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026/rank-19*

| Field | Value |
| --- | --- |
| Rank | #19 |
| 18m citations | 59 |
| Journal | Nature Communications |
| Year | 2024 |
| DOI | 10.1038/s41467-024-46787-7 |
| Corresponding authors | Yoshiho Ikeuchi |
| Institution | The University of Tokyo, Japan |

**Ranking page:** [Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026](https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026)

**Paper link:** [10.1038/s41467-024-46787-7](https://doi.org/10.1038/s41467-024-46787-7)

## Topics

Brain organoid · inter-regional cortical tract · inter-organoid axonal connections · reciprocal axon projections · oscillatory activity · network activity · Optogenetics · activity entrainment · short-term plasticity · macroscopic circuit · in vitro neural tissue model · axon bundles · neural circuit integration · directly fused organoids · structural hub · organoid-circuits

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuroscience and Neuropharmacology Research Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuroscience-and-neuropharmacology-research/2026. Accessed 2026-07-15.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```