# GLP-1R–positive neurons in the lateral septum mediate the anorectic and weight-lowering effects of liraglutide in mice

*PRI Rank #8 · Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026*

*Canonical URL: https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026/rank-8*

| Field | Value |
| --- | --- |
| Rank | #8 |
| 18m citations | 39 |
| Journal | Journal of Clinical Investigation |
| Year | 2024 |
| DOI | 10.1172/jci178239 |
| Corresponding authors | Yingjie Zhu |
| Institution | Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, China |

**Ranking page:** [Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026](https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026)

**Paper link:** [10.1172/jci178239](https://doi.org/10.1172/jci178239)

## Topics

liraglutide · GLP-1 receptor · GLP-1R-positive neurons · lateral septum · LSGLP-1R neurons · Food intake inhibition · weight-loss effects · Chemogenetic manipulation · Food intake inhibition · GLP-1 receptor knockdown · hypothalamus · Body weight regulation · naturalistic feeding episodes · synaptic inactivation · energy homeostasis

## Cite this ranking

```
Pepkio Research Index (PRI). Topics and Trends in Most Cited Neuropeptides and Animal Physiology Papers, Class of 2026. https://pri.pepkio.com/top-papers/neuropeptides-and-animal-physiology/2026. Accessed 2026-07-31.

Zheng Su, Tinsley Li, Thematic Shifts in Early-High-Impact Cancer Genomics and Diagnostics Research: A Bibliometric and Semantic Analysis. bioRxiv 2026.07.04.736459; doi: https://doi.org/10.64898/2026.07.04.736459
```